What is NMN?

What is NMN?

What is NMN? What are differences between NMN and NR? Can I still take NMN if I … … You one stop page for all your NMN questions.

What is NMN, and what does NMN stand for? 

Nicotinamide mononucleotide ("NMN", "NAMN", and "β-NMN") is a nucleotide derived from ribose and nicotinamide. Like nicotinamide riboside, NMN is a derivative of niacin, and humans have enzymes that can use NMN to generate nicotinamide adenine dinucleotide (NADH).

What Can NMN do?

NMN has been studied in animal models as a potential neuroprotective and anti-aging agent. Dietary supplement companies have aggressively marketed NMN products claiming those benefits.

Dietary supplement companies typically argues that NMN is a precursor to NAD+, or nicotinamide adenine dinucleotide, meaning it becomes NAD+ through a series of chemical transformations. NAD+ is a critical found in every cell of your body, but levels of NAD+ naturally fall with age, making it — and NMN, as a result — crucial.

Is NMN safe?

Doses of up to 500 mg was shown safe in men in a recent human study at Keio University School of Medicine, Shinjuku, Tokyo Japan. The research was conducted on healthy Japanese males via oral administration.  The single oral administration of NMN did not cause any specific deleterious effects in healthy men.

The results of laboratory analysis of blood and urine did not show any significant changes before and after NMN administration, except for serum bilirubin, creati‐ nine, chloride, and glucose levels. Whereas the serum levels of bilirubin significantly increased by 51.3%, the levels of glucose, creatinine, and chloride significantly decreased by 11.7%, 5.1%, and 2.3%, respectively, at 300 min at all doses from the baseline. These changes stayed within normal ranges, independent of the dose of NMN.

What are differences between NMN and NR

The biggest, and most obvious, difference between NMN and NR is size. NMN is simply larger than NR, meaning it often needs to be broken down to fit into the cell. NR, when compared to other NAD+ precursors (like nicotinic acid or nicotinamide) reigns supreme in efficiency. NR and NMN are both beneficial because they elevate levels of NAD+, which decline with age. NAD+ is vital to cellular metabolism, turning nutrients into cellular energy, and it also activates sirtuins, a set of proteins that regulate cellular health.

Can NMN help with sleep?

NMN could surely help with sleep. Increasing NAD+ synthesis can help with circadian rhythms, which could be beneficial for sleep.

Can NMN reverse hair loss?

NMN is still in clinical for humans so there's no evidence for a lot of the stuff we see in mice for people. So to answer your question no one knows, but mice reversed hair loss. 

Can I take NMN if I am pregnant ?

Please consult with your physician before taking any supplements if you are pregnant.

What is the best source for NMN? 

Laybio for sure, but because of tight capacity we are not open to individual purchase for now.

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